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Eye (Lond) ; 37(12): 2548-2553, 2023 08.
Artigo em Inglês | MEDLINE | ID: mdl-36572748

RESUMO

OBJECTIVES: We describe the real-world outcomes of photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSCR) in a single centre over nine years. METHODS: We carried out a retrospective analysis of patients with chronic CSCR who received half dose PDT in a single centre between 2011 and 2019. Visual acuity (VA) and retinal thickness (RT) was recorded between baseline visit and first recorded review visit. RESULTS: We included 125 eyes of 113 patients in this study. Mean age at treatment was 55.0 ± 12.1 years, with a higher male predominance (83 men, 30 women). Mean baseline VA was 0.40 ± 0.31 logMAR with a mean visual outcome gain post-PDT of 0.05 logMAR (p = 0.005). Mean baseline RT was 390 ± 82 microns with a mean reduction of RT post-PDT of 66 microns (p < 0.001). 17.6% of eyes were treated for recurrent CSCR. CONCLUSION: We found overall a mean improvement in VA and structural outcomes after PDT. In the absence of randomised clinical trials this study supports the use of half dose PDT for treatment of chronic CSCR.


Assuntos
Coriorretinopatia Serosa Central , Fotoquimioterapia , Porfirinas , Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Fármacos Fotossensibilizantes/uso terapêutico , Verteporfina/uso terapêutico , Coriorretinopatia Serosa Central/tratamento farmacológico , Estudos Retrospectivos , Porfirinas/uso terapêutico , Tomografia de Coerência Óptica , Doença Crônica , Angiofluoresceinografia
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